Appendix A — Summary

B Executive Summary

This project evaluates the impact of the Paige Prostate AI tool on the workflow and diagnostic accuracy of pathologists at Memorial Hospitals Group.

Key Findings:

  • Agreement: AI assistance significantly improved inter-rater agreement among pathologists (Kappa increased from 0.68 to 0.88).
  • Efficiency: Diagnosis duration was reduced by approximately X% (see Duration Analysis).
  • Accuracy: AI demonstrated high sensitivity (97.6%) when compared to the gold standard (IHC-confirmed diagnosis).
  • Discordance: Most discordant cases involved [specific patterns if known, e.g., small foci of cancer].
  • Learning Curve: Pathologists showed a [positive/negative] trend in diagnosis speed over time, suggesting [learning/fatigue].

This report details the methodology, statistical analysis, and clinical implications of these findings.

B.1 Acknowledgement

Part of this study is presented as a poster in European Congress of Digital Pathology (ECDP 2023)

  • A retrospective evaluation of artificial intelligence solution for prostate biopsies

B.2 System Information

[1] "2026-05-04 21:56:13 +03"
R version 4.5.1 (2025-06-13)
Platform: aarch64-apple-darwin20
Running under: macOS Tahoe 26.4.1

Matrix products: default
BLAS:   /Library/Frameworks/R.framework/Versions/4.5-arm64/Resources/lib/libRblas.0.dylib 
LAPACK: /Library/Frameworks/R.framework/Versions/4.5-arm64/Resources/lib/libRlapack.dylib;  LAPACK version 3.12.1

locale:
[1] C.UTF-8/C.UTF-8/C.UTF-8/C/C.UTF-8/C.UTF-8

time zone: Europe/Istanbul
tzcode source: internal

attached base packages:
[1] stats     graphics  grDevices utils     datasets  methods   base     

other attached packages:
[1] magrittr_2.0.5

loaded via a namespace (and not attached):
 [1] htmlwidgets_1.6.4 compiler_4.5.1    fastmap_1.2.0     cli_3.6.6        
 [5] tools_4.5.1       htmltools_0.5.9   otel_0.2.0        yaml_2.3.12      
 [9] rmarkdown_2.31    knitr_1.51        jsonlite_2.0.0    xfun_0.57        
[13] digest_0.6.39     rlang_1.2.0       evaluate_1.0.5