20  Case Level

20.1 Diagnosis Case Level

20.1.1 Benign, Suspicious, Malignant, agreement among 4 pathologist, case level, noAI

Note for Pathologists: Inter-rater agreement among the 4 pathologists at the case level, WITHOUT AI assistance.


 INTERRATER RELIABILITY

 Interrater Reliability                        
 ───────────────────────────────────────────── 
                  Fleiss' Kappa for m Raters   
 ───────────────────────────────────────────── 
   Subjects                               60   
   Raters                                  4   
   Agreement %                      55.00000   
   Kappa                           0.5416691   
   z                                14.08069   
   p-value        < .0000001   
 ───────────────────────────────────────────── 

20.1.2 Benign, Suspicious, Malignant, agreement among 4 pathologist, case level, withAI

Note for Pathologists: Inter-rater agreement among the 4 pathologists at the case level, WITH AI assistance.


 INTERRATER RELIABILITY

 Interrater Reliability                        
 ───────────────────────────────────────────── 
                  Fleiss' Kappa for m Raters   
 ───────────────────────────────────────────── 
   Subjects                               60   
   Raters                                  4   
   Agreement %                      80.00000   
   Kappa                           0.7983975   
   z                                18.24460   
   p-value        < .0000001   
 ───────────────────────────────────────────── 

20.1.3 Pathologist 1, case level, noAI vs withAI

Note for Pathologists: Comparing Pathologist 1’s diagnoses between no-AI and with-AI modes at the case level.

AI
Total
noAI withAI
Diagnosis


    Benign 5 (8.3%) 17 (28%) 22 (18%)
    Malignant 34 (57%) 36 (60%) 70 (58%)
    Suspicious 21 (35%) 7 (12%) 28 (23%)
Total 60 (100%) 60 (100%) 120 (100%)

Note for Pathologists: Alluvial plot showing how Pathologist 1’s diagnoses shifted (or stayed the same) when using AI.

20.1.4 Pathologist 2, case level, noAI vs withAI

Note for Pathologists: Comparing Pathologist 2’s diagnoses between no-AI and with-AI modes at the case level.

AI
Total
noAI withAI
Diagnosis


    Benign 20 (33%) 22 (37%) 42 (35%)
    Malignant 34 (57%) 35 (58%) 69 (58%)
    Suspicious 6 (10%) 3 (5.0%) 9 (7.5%)
Total 60 (100%) 60 (100%) 120 (100%)

Note for Pathologists: Alluvial plot showing how Pathologist 2’s diagnoses shifted when using AI.

20.1.5 Pathologist 3, case level, noAI vs withAI

Note for Pathologists: Comparing Pathologist 3’s diagnoses between no-AI and with-AI modes at the case level.

AI
Total
noAI withAI
Diagnosis


    Benign 16 (27%) 23 (38%) 39 (33%)
    Malignant 33 (55%) 34 (57%) 67 (56%)
    Suspicious 11 (18%) 3 (5.0%) 14 (12%)
Total 60 (100%) 60 (100%) 120 (100%)

Note for Pathologists: Alluvial plot showing how Pathologist 3’s diagnoses shifted when using AI.

20.1.6 Pathologist 4, case level, noAI vs withAI

Note for Pathologists: Comparing Pathologist 4’s diagnoses between no-AI and with-AI modes at the case level.

AI
Total
noAI withAI
Diagnosis


    Benign 12 (20%) 20 (33%) 32 (27%)
    Malignant 34 (57%) 35 (58%) 69 (58%)
    Suspicious 14 (23%) 5 (8.3%) 19 (16%)
Total 60 (100%) 60 (100%) 120 (100%)

Note for Pathologists: Alluvial plot showing how Pathologist 4’s diagnoses shifted when using AI.

20.2 Durations Case Level

20.3 Pathologist 1 Duration, Case Level

Note for Pathologists: Descriptive statistics for Pathologist 1’s total case duration (sum of all cores) with vs. without AI.


 DESCRIPTIVES

 Descriptives                                                         
 ──────────────────────────────────────────────────────────────────── 
                         P1_noAI_total_time    P1_withAI_total_time   
 ──────────────────────────────────────────────────────────────────── 
   N                                     60                      60   
   Missing                                0                       0   
   Mean                            511.1263                592.9698   
   Median                          451.9945                506.6940   
   Mode                            200.0950                234.5120   
   Standard deviation              240.4353                288.3290   
   Minimum                         200.0950                234.5120   
   Maximum                         1139.152                1820.550   
 ──────────────────────────────────────────────────────────────────── 

Note for Pathologists: Visual comparison (paired boxplot) of Pathologist 1’s case duration with vs. without AI.

20.4 Pathologist 2 Duration, Case Level

Note for Pathologists: Descriptive statistics for Pathologist 2’s total case duration with vs. without AI.


 DESCRIPTIVES

 Descriptives                                                         
 ──────────────────────────────────────────────────────────────────── 
                         P2_noAI_total_time    P2_withAI_total_time   
 ──────────────────────────────────────────────────────────────────── 
   N                                     60                      60   
   Missing                                0                       0   
   Mean                            610.1223                566.7121   
   Median                          616.3115                573.4965   
   Mode                            187.5500                206.4120   
   Standard deviation              217.5722                189.6036   
   Minimum                         187.5500                206.4120   
   Maximum                         1144.285                1006.171   
 ──────────────────────────────────────────────────────────────────── 

Note for Pathologists: Visual comparison (paired boxplot) of Pathologist 2’s case duration with vs. without AI.

20.5 Pathologist 3 Duration, Case Level

Note for Pathologists: Descriptive statistics for Pathologist 3’s total case duration with vs. without AI.


 DESCRIPTIVES

 Descriptives                                                         
 ──────────────────────────────────────────────────────────────────── 
                         P3_noAI_total_time    P3_withAI_total_time   
 ──────────────────────────────────────────────────────────────────── 
   N                                     60                      60   
   Missing                                0                       0   
   Mean                            598.4538                526.9725   
   Median                          558.4995                458.5675   
   Mode                            301.4210                231.5910   
   Standard deviation              211.9250                238.3500   
   Minimum                         301.4210                231.5910   
   Maximum                         1042.310                1275.880   
 ──────────────────────────────────────────────────────────────────── 

Note for Pathologists: Visual comparison (paired boxplot) of Pathologist 3’s case duration with vs. without AI.

20.6 Pathologist 4 Duration, Case Level

Note for Pathologists: Descriptive statistics for Pathologist 4’s total case duration with vs. without AI.


 DESCRIPTIVES

 Descriptives                                                         
 ──────────────────────────────────────────────────────────────────── 
                         P4_noAI_total_time    P4_withAI_total_time   
 ──────────────────────────────────────────────────────────────────── 
   N                                     60                      60   
   Missing                                0                       0   
   Mean                            591.2028                647.9873   
   Median                          515.5540                528.5525   
   Mode                            198.7370                283.1880   
   Standard deviation              311.9181                313.8058   
   Minimum                         198.7370                283.1880   
   Maximum                         1666.866                1528.933   
 ────────────────────────────────────────────────────────────────────